With Interseller sequences, you can customize each sequence that sends on its own timezone and schedule. It's a really good way to separate your EST leads vs your PST leads.
To get started, select the sequence and click on "Settings".
Then click on the "Schedule" tab when the pop-up appears. Toggle on the "Customize Schedule" switch which to open up a scheduling box that'll apply to only this sequence.
Save your schedule and you're all set!