The first thing to understand is your email schedule. Your email schedule can be found in settings under the schedule tab.
The email schedule feature determines when it's appropriate for us to send emails on your behalf. You can adjust your email schedule at an account and sequence level. If you don't have a custom schedule for each of your email sequences, your sequences will follow your default email schedule in your settings.
This is how the email schedule will appear in your account settings. You'll see the the timezone your email schedule is based in, your default email schedule, and the holidays feature.
You can toggle the holidays feature on if you don't want emails to be sent during U.S. holidays.
You can also adjust the timezone your email sequences are based in at an account and sequence level. Your emails will follow the default timezone set in your account settings if they don't have a custom timezone in each sequence.